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Seminar Schedule

Journal Clubs and Seminar Schedule 2009-2010

Time & Location - 11:00 am, 204-A EEB

Journal Clubs Schedule
Sep 3 New school year development and perspective of Prion Centre - Dr. David Westaway, et al
Sep 10 Wild-type Shadoo proteins convert to amyloid-like forms under native condition - Dr. Nathalie Daude
Sep 17 Intellectual Property at U of Alberta - Joanna Preston, Manager, Tech Transfer (Health Sciences)
Sep 24 Transmission and spreading of tauopathy in transgenic mouse brain - Dr. Satyabrata Kar
Oct 1 Functionally relevant domains of the prion protein identified in vivo - Dr. Sacha Genovesi
Oct 6 Meeting update from Prion 2009, Chalkidiki, Greece - Dr. David Westaway
Oct 15 Overview of the VLS: A Human Research Platform for Testing Genetic and Epigenetic Associations with Healthy Aging, Mild Cognitive Impairment, and sporadic Alzheimer's Disease - Dr. Roger A. Dixon & Dr. Stuart W.S. MacDonald
Oct 22 Multiscale modeling of misfolding and aggregation of amyloidogenic proteins - Dr. Andriy Kovalenko (Video Conference)
Oct 29 Walking around Shadoo biology: behaviour in prion infection, cleavage sites and neuroprotection - Dr. Sacha Genovesi
Nov 5 Journal Club: Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain - Presenter: Mahua Maulik
Nov 12 Could the species-barrier of TSEs be explained by species-specific plasma co-factors involved in misfolding and/or propagation of misfolded prion proteins? - Dr. Norman Neumann (Video Conference)
Nov 19 Journal Club: S-Nitrosylation of Drp1 Mediates β-Amyloid–Related Mitochondrial Fission and Neuronal Injury - Cho DH et al, Science, 2009 – Presenter: Dr. SangGyun Kang
Nov 26 Genetic and metabolic triggers of Alzheimer's disease neuropathogenesis - Dr. David Vergote
Dec 3 Developing Novel Zebrafish Models to Investigate Neurological Diseases - Dr. Ed Burton, University of Pittsburgh
Dec 10 Special seminar: Building Operations in CPPFD - Ned Chisholm
Dec 17 The long and short of it: Telomeres, nutrition and Alzheimer's disease - Dr. Nathan O'Callaghan
Jan 14 The Molecular Response to Prion Infection – Laura Moody, University of Wisconsin
Jan 21 Journal Club: Darwinian Evolution of Prions in Cell Culture Li J et al, Science, 2009 – Presenter: Dr. Valerie Fleish
Jan 28 Regulation of PrPSc Propagation by the Plasmin(ogen) System - Charles Mays, University of Kentucky
Feb 4 Journal Club: A Novel, Drug-based, Cellular Assay for the Activity of Neurotoxic Mutants of the Prion Protein Massignan T et al, J Biol Chem, 2009 – Presenter: Dr. Nathalie Daude
Feb 11 Journal Club: Neuroprotective Function of Cellular Prion Protein in a Mouse Model of Amyotrophic Lateral Sclerosis - Steinacker P et al, Am j Pathol, 2010 – Presenter: Agnes Lau
Feb 18 Journal Club: Axonal Prion Protein is Required for Peripheral Myelin Maintenance - Bremer J et al, Nat Neurosci, 2010 - Presenter: Dr. Allen Herbst
Feb 25 Beta-Amyloid (Abeta) Activation of Mouse Basal Forebrain Neurons is Mediated by Prion Proteins – Dr. Kwai Alier
Mar 4 Journal Club: Reduced IGF-1 Signaling Delays Age-Associated Proteotoxicity in Mice - Cohen E et al, Cell, 2009 – Presenter: Dr. David Vergote
Mar 11 Journal Club: Alcadein cleavages by APP a-and g-secretases generate small peptides p3-Alcs indicating Alzheimer disease-related g-secretase dysfunction – Hata S et al, J Biol Chem, 2009 – Presenter: Dr. Laura Edwards-Ingram
Mar 18 Social Science Cafe: Discussing Implications of Live Testing (Video Conference)
Mar 25 Meeting update from PrP Canada
Apr 1 Influence of cholesterol sequestration on Alzheimer's Disease pathology: evidence from a novel transgenic mouse model overexpressing APP in the absence of Npc1 protein- Mahua Maulik; Probing the differential stability of the prion protein by NMR– Olivier Julien
Apr 8 Is there a role for prion protein in pain and depression? – Dr. Vinicius Gadotti, University of Calgary (Videoconference)
Apr 15 Processing and functional roles of the major isoforms of the Alzheimer's amyloid precursor protein – Dr. Tim Revett
Apr 22 The role of copper in the processing of PrP – Agnes Lau; Dysregulation of protein synthesis regulatory pathways by cytoplasmic PrP mutants - Rory Shott
Apr 29 Alterations of the microRNA network in prion diseases – Dr. Stephanie Booth – Public Health Agency of Canada, Winnipeg (Video Conference)
May 6 Using Zebrafish as a tool to study proteins involved in Alzheimer Disease - Darcy Kaiser; Amyloid beta peptide neurotoxicity: is cholesterol sequestration a cause or just a sign? - Amany Mohamed
May 13 Solute transporter membrane proteins: looking around the neighbourhood – Dr. Joe Casey
May 20 No seminar – FoMD Research Day
May 27 Proteomic Profiling of Sera from Mice infected with Prion Disease – Dr. Allen Herbst
Jun 3 Special seminar: Biosafety in the CPPFD TSE Containment Spaces – Dr. Daniel Dragon
Jun 10 Development and applications of LC/MS methods for comprehensive proteome and metabolome analysis – Dr. Liang Li
Jun 17 Lentiviral Delivery of MicroRNA Targeting PrPc – Dr. Sanggyun Kang


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